Cardiopulmonary function in rats with lung hemorrhage induced by pulsed ultrasound exposure.
نویسندگان
چکیده
منابع مشابه
Cardiopulmonary function in rats with lung hemorrhage induced by pulsed ultrasound exposure.
OBJECTIVE To assess cardiopulmonary function in rats exposed to pulsed ultrasound using superthreshold exposure conditions known to produce significant lung hemorrhage. METHODS In 1 group of 9 anesthetized Sprague-Dawley rats, 5 foci of ultrasound-induced hemorrhage were produced in the left lung of each rat. In a second group of 6 rats, 5 foci of ultrasound-induced hemorrhage were produced i...
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In animal experiments, the pathogenesis of lung hemorrhage due to exposure to clinical diagnostic levels of ultrasound has been attributed to an inertial cavitation mechanism. The purpose of this article is to report the results of two experiments that directly contradict the hypothesis that ultrasound-induced lung hemorrhage is caused by inertial cavitation. Elevated hydrostatic pressure was u...
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The pressure threshold of ultrasound-induced lung hemorrhage has been estimated as a function of pulse duration (PD) in adult rats. A total of 220 10to 11week-old 250-gram female Sprague-Dawley rats (Harlan) were randomly divided into 20 ultrasonically exposed groups (10 rats/group) and one sham group (20 rats). The 20 ultrasonically exposed groups (2.8 MHz; 10-s exposure duration; 1-kHz PRF) w...
متن کاملThreshold estimation and superthreshold behavior of ultrasound-induced lung hemorrhage in rats: role of age dependency.
Age-dependent threshold and superthreshold behaviors of ultrasound-induced lung hemorrhage were investigated with one hundred ten 12.6 +/- 0.8-d-old rats, one hundred ten 22.9 +/- 0.8-d-old rats, and one hundred 57.7 +/- 3.9-d-old rats. Exposure conditions were: 2.8 MHz, 10-s exposure duration, 1-kHz pulse repetition frequency and 1.3-mus pulse duration. The in situ (at the pleural surface) pea...
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ژورنال
عنوان ژورنال: Journal of Ultrasound in Medicine
سال: 2001
ISSN: 0278-4297
DOI: 10.7863/jum.2001.20.11.1197